A Neuroscientist’s Quest to Reverse Engineer the Human Brain: Scientific American

“Yet for many mental disorders, such as autism and schizophrenia, a clear and consistent pathology of the brain has not been found. Why? Researchers have conjectured that the individual neurons are healthy, but they are connected with each other in an abnormal pattern. Unfortunately, such “miswirings” or “connectopathies” have remained merely hypothetical, because our technologies for mapping neural connections have been too primitive.”